CHEMICAL COMPOSITION AND ACETYLCHOLINESTERASE ACTIVITY OF Syzygium pyrifolium (Blume) DC. ESSENTIAL OIL

Authors

  • Nur Hazwanie Abdul Kadir
  • Wan Mohd Nuzul Hakimi Wan Salleh ​Department of Chemistry Faculty of Science and Mathematics Universiti Pendidikan Sultan Idris
  • Nurunajah Ab Ghani
  • Shamsul Khamis
  • Mohd Afiq Aizat Juhari

DOI:

https://doi.org/10.52292/j.laar.2023.1121

Keywords:

essential oil, Myrtaceae, Syzygium pyrifolium, GC-MS, geraniol, cholinesterase

Abstract

This study aims to investigate the chemical composition and acetylcholinesterase activity of essential oil from Syzygium pyrifolium leaves. The essential oil was obtained by hydrodistillation in a Clevenger-type apparatus and its chemical composition was analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Thirty-two volatile components were identified in S. pyrifolium leaves oil, including geraniol (73.8%), ?-pinene (7.0%), ?-pinene (5.7%) and (E)-?-ocimene (4.5%) as the major components. Acetylcholinesterase activity was evaluated using Ellman method and the essential oil showed strong inhibitory activity (I%: 82.5%). Our findings demonstrate that S. pyrifolium essential oil could be useful for an alternative raw material of food and medicinal products for pharmaceutical applications.

Published

2023-07-18