PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL ACTIVITIES OF HELIOTROPIUM CURASSAVICUM LINN

Authors

  • W. WASIULLAH
  • Saleem JAN
  • A. A. SHAD
  • A. BASIT
  • F. ULLAH

DOI:

https://doi.org/10.52292/j.laar.2019.369

Keywords:

DPPH, ABTS

Abstract

The current study was focused on the phytochemical investigation and pharmacological activities of the various fractions (methanolic crude, defatted methanolic, n-hexane, dichloromethane, ethylacetate and water) of H. curassavicum. The various plant extracts were examined for the total phenolic contents by taking Gallic acid as a standard, antioxidant scavenging assay by using DPPH (2, 2diphenyl-1-picrylhydrazy) & ABTS [2, 2-azinobis (3ethylbenzthiazoline-6-sulphonic acid)] free radicals, antifungal assay by using Terbinafine solution in DMSO as positive control and pure DMSO as negative control and in-vitro antibacterial activity. Methanolic crude extract showed high phenolic contents and significant antioxidant activity (both DPPH & ABTS). All other fractions were also found to have significant potential.

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Published

2019-03-29

Issue

Vol. 49 No. 2 (2019): Latin American Applied Research

Section

Applied Chemistry

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