PASSIVITY BASED FRACTIONAL ORDER ADAPTIVE CONTROL OF DEPTH OF ANESTHESIA

Authors

  • M. BOROOJERDI ALAVI
  • M. TABATABAEI

DOI:

https://doi.org/10.52292/j.laar.2019.337

Keywords:

Fractional-order adaptation mechanism, Passivity based controller, Depth of anaesthesia, Model reference adaptive controller

Abstract

In this paper, a passivity based model reference adaptive controller with fractional-order adaptation mechanism is utilized for control of depth of anesthesia. The propofol infusion rate is adjusted to reach an appropriate Bispectral Index (BIS). The Pharmacokinetic-Pharmacodynamic (PK-PD) model is employed to model the distribution of propofol in patient body. Since, the PK-PD model parameters depend on physical specifications of patient, employing an adaptive controller to control this system is inevi-table. The utilized controller is a pole placement con-troller in which its polynomial coefficients are ad-justed according to a fractional-order adaptation mechanism. Simulation results on several patients demonstrate the efficiency of the proposed method in the presence of disturbance, noise, and model uncertainties.

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Published

2019-07-31

Issue

Vol. 49 No. 3 (2019): Latin American Applied Research

Section

Control and Information Processing

License

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